Innovative solutions for 340B and beyond

Macro Helix helps covered entities and contract pharmacies manage their successful 340B programs, so they can assist patients in receiving comprehensive healthcare.

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340B Contract Pharmacist stocking medications on shelves

Using technology for good

Advancing healthcare outcomes for all

Our technology helps covered entities and contract pharmacies manage their 340B Drug Pricing Program with greater simplicity and effectiveness. We help our customers focus on what they do best - provide the best possible care to every patient. We fill the gaps that other third-party administration providers cannot by offering the most complete solution in the pharmacy industry.

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Who we serve

We equip pharmacy leaders and their staff at health systems, hospitals, clinics and retail settings with proven 340B pharmacy management solutions and expert guidance to run an agile, effective and efficient pharmacy.


340B Covered Entities

Learn how hospitals, clinics and health systems maximize the value of their 340B program with Macro Helix.

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Pharmacy Manager from 340B Covered Entity

340B Contract Pharmacies

Discover how Macro Helix helps retail providers join our reliable contract pharmacy network to support their 340B program.

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healthcare providers are able to deliver care to patients through 340B program

We serve0

covered entity clients in 48 states


of 340B-eligible hospitals in the U.S. partner with Macro Helix

"My team is in Architect on a daily basis running reports, validating data, working through our crosswalks and catalogs. Our most recent implementation experience at our downtown hospital in Denver, Colorado, was our best yet."

Ashley M. Espinosa

System Pharmacy Manager, SCL Health

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"With Macro Helix on site and in the room, it really enabled us to do all the things that need to be done during an audit quickly and efficiently… It’s one of the best decisions you can make!"

Eileen Kelly

Director, Revenue Cycle Analysis, Einstein Healthcare Network (EHN), Philadelphia, Pennsylvania

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"I didn’t realize Macro Helix would do all this for us. I was very pleasantly surprised! We felt very confident prior to the audit that we had things in place to prove we are compliant."

Amanda Mather

PharmD, RPh, Director of Pharmacy, Shenandoah Medical Center (SMC), Shenandoah, Iowa

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Hear what our customers say about 340B Architect

"We had a lot of quick learning to do about 340B. Having an expert like Macro Helix that could come in and educate us and then help get our program off the ground was exceptionally helpful."

Chris Jellison

Corporate Director of Pharmacy, Parkview Health

"Macro Helix has helped us immensely, in terms of optimizing and maintaining a compliant program."

Gary Kerr

Chief Pharmacy Officer, Baystate Health

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Macro Helix solutions

Macro Helix’s 340B administration software, 340B Architect, empowers covered entities to support healthcare equity in their community.

We offer our customers options to help start, optimize or expand their 340B program

Intelligent 340B solutions and services

340B Central Split and 340B Order Optimizer

Covered entity-owned pharmacies can compliantly split orders across purchasing accounts so they can be shipped to a central location. Orders can be split based on your ordering preferences for price and available accumulations.

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Compliantly centralize and split pharmacy orders across accounts to centralized location

340B Impact

Advanced data and analytics capabilities to enable informed, intelligent purchasing decisions for joint McKesson and Macro Helix customers.

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Advanced data and analytics capabilities to enable informed, intelligent purchasing decisions for joint McKesson and Macro Helix customers

340B Gateway

Retail chain 340B program management that consolidates the functions of multiple 340B processors down to one, while allowing covered entities to retain their processor of choice.

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retail pharmacy chain solves common challenges of administering a 340B contract

340B Program Audit Support

Our highly experienced Audit Support team provides your covered entity with the ongoing assistance necessary to prepare for and maintain a compliant 340B program.

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Maintain a compliant 340B program with assistance and technology of Audit Support

340B RxCorrelate

Helping covered entities optimize their 340B savings by identifying prescriptions that may have resulted from a referral to an outside provider.

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receive medications at a savings through 340B program

340B Architect

With full access to your covered entity’s data, you can manage and optimize your contract pharmacy network all from a single integrated platform.

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dispense 340B medications in your hospital and via a retail contract pharmacy from the same platform

340B Validate

An intelligent module that supports compliance and provides validation of your 340B prescriptions that generate a rebate request—without revealing your identity or data as a covered entity. Also, set up exclusions and do not order lists.

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Manufacturer safely and securely receives validation of your prescriptions for 340B rebates

Community Prescription Assistance

A flexible, auditable program delivering 340B savings directly to the patient.

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Patient savings

Unlimited potential

Do more with Macro Helix

Improve financial performance
Create operational efficiency
Maintain regulatory compliance
Optimize your pharmacy workflow
Reduce barriers for people to get care
Meet the needs of vulnerable patients

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Interested Solutions