Innovative solutions for 340B and beyond
Macro Helix helps covered entities and contract pharmacies manage their successful 340B programs, so they can assist patients in receiving comprehensive healthcare.
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Using technology for good
Advancing healthcare outcomes for all
Our technology helps covered entities and contract pharmacies manage their 340B Drug Pricing Program with greater simplicity and effectiveness. We help our customers focus on what they do best - provide the best possible care to every patient. We fill the gaps that other third-party administration providers cannot by offering the most complete solution in the pharmacy industry.
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Who we serve
We equip pharmacy leaders and their staff at health systems, hospitals, clinics and retail settings with proven 340B pharmacy management solutions and expert guidance to run an agile, effective and efficient pharmacy.
340B Covered Entities
Learn how hospitals, clinics and health systems maximize the value of their 340B program with Macro Helix.

340B Contract Pharmacies
Discover how Macro Helix helps retail providers join our reliable contract pharmacy network to support their 340B program.

covered entity clients in 48 states
of 340B-eligible hospitals in the U.S. partner with Macro Helix
play_circle Watch the video"Macro Helix has helped us immensely, in terms of optimizing and maintaining a compliant program."
play_circle Watch the video"My team is in Architect on a daily basis running reports, validating data, working through our crosswalks and catalogs. Our most recent implementation experience at our downtown hospital in Denver, Colorado, was our best yet."
play_circle Read the case study"With Macro Helix on site and in the room, it really enabled us to do all the things that need to be done during an audit quickly and efficiently… It’s one of the best decisions you can make!"
play_circle Read the case study"I didn’t realize Macro Helix would do all this for us. I was very pleasantly surprised! We felt very confident prior to the audit that we had things in place to prove we are compliant."
Hear what our customers say about 340B Architect
"We had a lot of quick learning to do about 340B. Having an expert like Macro Helix that could come in and educate us and then help get our program off the ground was exceptionally helpful."
play_circle Watch the video"Macro Helix has helped us immensely, in terms of optimizing and maintaining a compliant program."
play_circle Watch the video"My team is in Architect on a daily basis running reports, validating data, working through our crosswalks and catalogs. Our most recent implementation experience at our downtown hospital in Denver, Colorado, was our best yet."
Macro Helix solutions
Macro Helix’s 340B administration software, 340B Architect, empowers covered entities to support healthcare equity in their community.
340B Architect is a complete program solution for covered entities
Learn more arrow_right_altWe offer our customers options to help start, optimize or expand their 340B program
Intelligent 340B solutions and services

340B Central Split and 340B Order Optimizer
Compliantly split orders across purchasing accounts for a central warehouse ordering process.


340B Impact
Advanced data and analytics capabilities to enable informed, intelligent purchasing decisions for joint McKesson and Macro Helix customers.


340B Gateway
Retail chain 340B program management that consolidates the functions of multiple 340B processors down to one, while allowing covered entities to retain their processor of choice.

340B Program Audit Support
Our highly experienced Audit Support team provides your covered entity with the ongoing assistance necessary to prepare for and maintain a compliant 340B program.


340B RxCorrelate
Helping covered entities optimize their 340B savings by identifying prescriptions that may have resulted from a referral to an outside provider.


340B Architect
With full access to your covered entity’s data, you can manage and optimize your contract pharmacy network all from a single integrated platform.

340B Validate
An intelligent module that supports compliance and provides validation of your 340B prescriptions that generate a rebate request—without revealing your identity or data as a covered entity. Also, set up exclusions and do not order lists.

Community Prescription Assistance
A flexible, auditable program delivering 340B savings directly to the patient.

Our pharmacy service portfolio can help maximize pharmacy operations to strengthen your organization’s financial viability, generate revenue and improve patient outcomes.
Learn more arrow_right_altUnlimited potential
Do more with Macro Helix
Improve financial performance
Create operational efficiency
Maintain regulatory compliance
Optimize your pharmacy workflow
Reduce barriers for people to get care
Meet the needs of vulnerable patients